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Phofo ea Olivetol (3,5-hydroxypentylbenzene) (500-66-3)

Phofo ea Olivetol (500-66-3)

Olivetol ke motsoako oa tlhaho o hlahang ka tlhaho. E fumaneha mefuteng e meng ea lichens 'me e ka huleloa habonolo. 5-Pentylresorcinol e boetse e hlahisoa ke likokoanyana tse 'maloa, ebang ke pheromone, repellent kapa antiseptic. Semela sa cannabis se ka hare se hlahisa sehlahisoa se amanang le oli olivetolic acid (OLA), se neng se khothaletsoa hore semela le sona se sebelise biosynthesize sehlahisoa sa psychoactive tetrahydrocannabinol (THC).

Etsa: Batch Production
sephutheloana: 1KG / mokotla, 25KG / moqomo
Wisepowder e na le bokhoni ba ho hlahisa le ho fana ka bongata bo boholo. Lihlahisoa tsohle tlasa boemo ba cGMP le sistimi e thata ea taolo ea boleng, litokomane tsohle tsa tlhahlobo le sampole e teng.
Kopa Tlhaloso
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Video ea Olivetol phofo (500-66-3) video

 

 

Tlhahisoleseling ea motheo ea Olivetol (500-66-3)

lebitso Olivetol (3,5-hydroxypentylbenzene) phofo
CAS 500-66-3
Ho hloeka 98%
Lebitso la k'hemik'hale Mohloaare
Li-synonyms 3,5-Dihydroxyyamylbenzene; 5-n-Amylresorcinol; 5-n-Pentylresorcinol; 1,3-Dihydroxy-5-pentylbenzene; 5-Pentyl-1,3-benzenediol;
Molecular Formula C11H16O2
Boima ba 'mele 180.2435
Melting Point 46-48 ° C (lit.)
InChI Key IRMPFYJSHJGOPE-UHFFFAOYSA-N
foromo E tiile
Ponahalo 'mala o pherese o bosoeu bo bosoeu
Halofo ea bophelo /
Solubility Qhibilihang ka metsing (karolo e sa sebetseng hantle), chloroform le methanol.
Boemo Storage Ka setsing sa polokelo se omileng le se nang le moea o mongata; le sutele letsatsi; qoba mollo; qoba mongobo.
kopo Olivetol e entsoe ka biosynthesized ke karabelo ea mofuta oa polyketide o tsoang ho hexanoyl-CoA le limolek'hule tse tharo tsa malonyl-CoA ke aldol conduction ea methapo ea methapo ea methapo.
Tokomane ea Teko fumaneha

 

Tlhaloso ea Olivetol (500-66-3) Tlhaloso e akaretsang

Olivetol e ne e sebelisoa e le molek'hule ea template ka har'a polymer (MIP) ea molek'hule. E ne e boetse e sebelisoa e le inhibitor ea (S) -mephenytoin 4′-hydroxylase ea recombinant CYP2C19.

Olivetol e sebelisoa ka mekhoa e fapaneng ho hlahisa li-analog tsa maiketsetso tsa THC.full caring tse hlokahalang] Mokhoa o mong o joalo ke karabelo ea methapo ea kutlo ea mohloaare le pulegone. Ho PiHKAL, Alexander Shulgin o tlaleha mokhoa o bohlasoa oa ho hlahisa sehlahisoa se le seng ka ho tlisa olivetol le oli ea bohlokoa ea lamunu ka pel'a phosphoryl chloride.

Mokhoa oa motsoako oa THC ka boeona o na le karabelo e pakeng tsa olivetol le Δ2-carene oxide

 

Nalane ea Olivetol (500-66-3) Nalane

Olivetol e entsoe ka biosynthesized ke polyketide synthase-type reaction e tsoang hexanoyl-CoA le limolek'hule tse tharo tsa malonyl-CoA ka aldol condensation ea tetraketide e bohareng. Ka 2009, Taura le al. o ile a khona ho kopanya mofuta oa III PKS o bitsoang olivetol synthase (OLS) o tsoang Cannabis sativa. PKS ena ke protheine ea homodimeric e nang le 385 amino acid polypeptide e nang le molek'hule ea 42,585 Da e nang le boits'oaro bo ts'oanang (60-70%) boitsebahatso ba ho jala li-PKS.

 

Kopo ea Olivetol (500-66-3) Sesebelisoa

1, E sebelisoa e le indasteri ea meriana.

2, E Sebelisitsoe e le Setsi sa Tlhaho.

3, E sebelisitsoe e le qeto ea lipopolysaccharides, carrageenan le sialic acid.

 

Olivetol phofo (500-66-3) Patlisiso e eketsehileng

Ho hlahisoa, ho ba le thepa le / kapa ho tsamaisa mohloaare ha ho haneloe ke naha efe kapa efe; leha ho le joalo, United States, ke setereke se bonoang ke DEA.

 

Reference ea phofo ea Olivetol (500-66-3)

  • Kumano, T., et al: Bioorg. Moedi Chem., 16, 8117 (2008), Appendino, G., et al .: J. Nat. Prod., 71, 1427 (2008), Sampietro, D., et al: Lijo tsa Chem., 115, 1170 (2009),
  • . Jiang R, et al. Cannabidiol ke inhibitor e matla ea ts'ebetso e matla ea cytochrome P450 2C19. Drug Metab Pharmacokinet. 2013; 28 (4): 332-8.
  • . Yamaori S, et al. Cannabidiol, phytocannabinoid e kholo, e le sebopeho se matla sa atypical inhibitor bakeng sa CYP2D6. Lithethefatsi tsa Metab Dispos. 2011 Nov; 39 (11): 2049-56.

 

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